Health is one of the most consequential domains for artificial intelligence. People are increasingly turning to AI for help in moments that matter: interpreting a confusing test result at midnight, deciding whether to seek urgent care, or supporting a loved one through a chronic condition. Better information and support can improve outcomes and make care more equitable.

This is where we demonstrate that our values – Kindness, Trust, Quality, Simplicity, Safety & Security, and Evaluation – are not just marketing slogans. They are operational principles that shape product design, engineering trade-offs, and the partnerships we pursue. We listen closely, test rigorously and improve constantly. That commitment shows up in how we build and evaluate models, how we present answers, and how we design user experiences that reduce anxiety rather than amplify it.

Our research on how people are using our AI to support their health makes the opportunity clear. Across Microsoft AI consumer products we handle tens of millions of health questions every day, and a recent deep analysis of half a million Copilot conversations shows people rely on AI for symptom interpretation, test result explanation, and practical care navigation. That scale and intimacy make health a uniquely important focus for MAI: the potential upside is enormous, and the responsibility is correspondingly high.

Our progress to date demonstrates our values in action. With Microsoft AI Diagnostic Orchestrator (MAI DxO), we showed how an AI system could significantly improve clinical reasoning in complex cases. In research settings, MAI DxO gets to the right answer to some of medicine’s most diagnostically complex and intellectually demanding cases, at an accuracy level above baseline models and the physician cohort we tested against.

Building on this work, our strategic collaboration with Mayo Clinic offers the prospect of making expert medical intelligence accessible to millions more who need it. Together we are developing a frontier AI model designed specifically for healthcare, bringing together Mayo Clinic’s world-leading healthcare expertise, clinical health data and longitudinal insights with our advanced AI, cloud, engineering and superintelligence capabilities. The resulting model will first be deployed within Mayo Clinic’s own environment, the world’s leading hospital system, and will aim to support a broad range of clinical reasoning and healthcare use cases, including earlier diagnoses, more personalized treatment decisions and better patient outcomes. Once validated, organizations worldwide will be able to access the frontier AI health model to better support patients, clinicians and consumers. The health model itself will be owned by Mayo Clinic, reinforcing our mutual commitment to patient trust, clinical rigor and responsible stewardship of clinical data and AI.

Advances in health intelligence must be matched by quality in product development and real world deployment. We recently opened Copilot Health in preview for Microsoft 365 Personal, Family, and Premium subscribers in the US – a phased rollout that will let us learn from real users while maintaining rigorous safety and evaluation. Copilot Health brings together your health records, wearable data, and health history into one place, then applies intelligence to turn them into a coherent story. Delivering value means designing for people: simple interfaces, clear citations, and explanations that help users act. We build trust by designing with representative users like the National Health Council while layering in safeguards and pursuing independent verification: Copilot Health’s development and governance is informed by hundreds of clinicians and external reviewers, and our processes have achieved ISO/IEC 42001 certification for AI management systems. These efforts compound: we expect the frontier AI model for healthcare we create with Mayo Clinic to enhance Copilot Health’s capabilities.

The work ahead is substantial, but the direction is clear. By grounding our work and partnerships in our core values, we have the potential to create trusted AI experiences that can help millions of people when it matters most. With rigorous science, intentional partnerships, and a relentless focus on the people we serve, we are committed to making that future real.

William Sieghart is a world-renowned patron of poetry, a best-selling author of the “Poetry Pharmacy” anthologies who helped establish National Poetry Day in the UK. But it is at his one-on-one “consultations” at events across the country where he brings the power of poetry to life.

During these sessions, participants describe what’s on their mind and William recommends a poem. His measured, warm and compassionate approach has resonated with thousands of people for whom he has prescribed poems.

William asked Microsoft AI to help him scale these sessions to a global audience. Ode Poetry, the result of this collaboration along with creative studio Gravity Road, leverages MAI’s state-of-the-art audio models to deliver a first-of-its-kind digital poetry experience.

“When William approached us with the concept for Ode Poetry, it felt like the perfect opportunity to bring our MAI audio models to life in a way that reflects our humanist-first values,” said Trevor Back, MAI product lead.

Ode Poetry asks you questions about how you’re feeling and recommends a poem that might resonate, playing a recording of a real person reading it. AI simply supports the connection between the listener, the creativity of the original poem, and its human reader. It does this through empathetic questions and a thoughtful approach to recommending poems based on William’s literary analysis.

The project presented an interesting technical challenge. In order to build a voice experience that responds empathetically to users in real time and recommends an appropriate poem, the system must:

• Listen carefully and understand any user
• Respond at the right time, in the right style
• Remain grounded in William’s unique style and poetry expertise

We used MAI’s voice models to power this experience, and worked closely with Ode to build custom solutions for their specific needs, including safety and response quality, all detailed below.

Speech understanding with MAI-Transcribe

Ode Poetry uses our MAI-Transcribe model to understand spoken language in real time. A leader in its class, it can handle the nuances and complexities of verbal communication, including the many languages, accents, dialects and styles people use today.

The data reflects this. The latest version of MAI-Transcribe achieves the lowest Word Error Rate (4.86%) of any competitor on the FLEURS benchmark, showcasing its ability to understand many languages and difficult audio examples (such as background noise). The model enables users to engage naturally rather than adapting their speech to the technology. Real-world use cases such as Ode Poetry demonstrate the model’s ability to work effectively in production environments.

Bringing expressive speech to conversational AI with MAI-Voice

Ode Poetry also uses MAI-Voice to re-create William’s distinctive vocal style. What makes MAI-Voice special is its ability to reproduce William’s speaking style with very high fidelity, using only a short sample of audio. Once you’ve heard William’s voice, you’ll understand why this is so important.

MAI-Voice’s capabilities were achieved by building our own large-scale multilingual data pipeline, augmented with high-fidelity studio recordings of voice talent. This enabled researchers to train a model with both the breadth to sound natural across contexts and the depth to faithfully reproduce any specific speaker. Here’s an example:

An audio sample showcasing the natural expressivness available with MAI-Voice.

Reasoning between conversation and poem recommendations

Ode Poetry is a unique conversational experience because it not only enables a natural conversation, but it also recommends a poem as an outcome, using the structured conditions William has provided for the poems in his “Poetry Pharmacy” books.

We developed a harness to distill William’s years of experience with personal consultations into a system that can match the unstructured conversation with the user into a framework that enables the right poem to be recommended. This system included carefully chosen deterministic logic and tool-calling mechanisms.

We also focused on responsible AI for a safe user experience; for example, experimenting with jailbreaks that can trick a language model into attempting real psychiatric diagnoses. Through an iterative approach of safety evals, red teaming, and guardrail updates, we were able to prevent a range of misaligned model behaviors.

Hill-climbing was also a critical component to achieving a premium editorial product. High-quality production AI systems hinge on countless small improvements. Accuracy, consistency, latency, reasoning, and expressiveness all contribute to the final result, and a fix in one dimension can cause regressions in another. We evaluated Ode Poetry across a wide range of emotional scenarios and used the results to iteratively refine prompts, recommendation logic and speech output. Achieving a consistently excellent result took relentless iteration of both text and audio prompts, and the shared commitment from both Microsoft AI and William’s team made this collaboration a joint act of creative care.

This is reflected in the app launching today. As William shared when he first began interacting with his digital extension: “One of [the researchers] recorded my introduction and the next thing I knew, he was playing my voice…and the intonation, the pauses…I just thought, wow, that’s quite nice.

“It’s really exciting for me,” he added, “because what we’re about to embark on together is in a way my lifetime’s ambition, which is to bring poetry to everyone.”

We invite you to try out the experience of a poetry session with William at Ode Poetry, and test the latest versions of our models at the MAI Playground.